Growing up in the streets of Dundee, actor Brian Cox was surrounded by tobacco. His entire family either smoked it or chewed it and yet Brian reveals, he never took up the habit. To find out why not, Brian travels to Virginia in the US to discover how the habit of smoking kick-started the British Empire and created a global market of addicts.
Giles Coren, the food critic takes up three extreme diet regimes in a bid to push the very limits of life expectancy. Giles's search to find a diet which might extend his life comes after his great-grandfather lived to the grand old age of 93. His grandfather passed away aged 76 and his father Alan died aged 69. The Coren men are bucking the global trend of living longer so Giles, now in his mid-forties, wants to find out what he can do to avoid a premature death.
Stem cells found in the bone marrow are crucial for our health because they are needed to become new blood cells that sustain and protect our bodies. But when the transformation goes wrong, harmful mutations can cause the cells to start replicating without control -- a type of cancer known as leukemia. Danilo Allegra and Dania Puggioni explain how this happens and how certain treatments provide hope for those suffering from the disease.
The first ever vaccine was created when Edward Jenner, an English physician and scientist, successfully injected small amounts of a cowpox virus into a young boy to protect him from the related (and deadly) smallpox virus. But how does this seemingly counterintuitive process work? Kelwalin Dhanasarnsombut details the science behind vaccines.
Follows two patients through groundbreaking 'first in-human' trials for CAR T-cell therapy, a treatment described as the beginning of the end of cancer. Not allowed to meet and separated by two floors of a hospital, 53-year-old Graham and 18-year old-Mahmoud are nevertheless bound together by their commitment to the treatment and their faith in the science. Terminally ill, the trial represents their only option. How do their ages and life experiences affect their physical and emotional response? For Martin Pule, the scientist who has developed the treatment, the responsibility of curing patients is both exciting and daunting. He knows he stands on the cusp of a breakthrough that could radically change the way we treat cancer. At the heart of this film is the complex relationship between the patients and the clinical team. How much hope can the patients be given when they are effectively going into these trials as human guinea pigs? The patients and clinical team must weigh up hope with realism and their response is a profound and revealing reflection of the human condition.
2019 • Health
Has anyone ever told you, “Stand up straight!” or scolded you for slouching at a family dinner? Comments like that might be annoying—but they’re not wrong. Your posture is the foundation for every movement your body makes and can determine how well your body adapts to the stresses on it. Murat Dalkilinç gives the pros of good posture.
Horizon investigates a new era of Alzheimer's research, which is bringing hope to millions of sufferers across the world. New scanning and gene technology is allowing scientists to identify the disease at its earliest stages, often 15 years before symptoms appear and the brain cells are destroyed. A series of new drugs trials in Colombia, the USA and Europe are showing startling success in reducing beta amyloid, the protein which is a hallmark of the disease. It is also becoming clear that changes in lifestyle can prevent the development of the disease. A new system inside the brain has been discovered which clears amyloid when we are in deep sleep, but allows it to accumulate if we don't sleep well. The programme reveals that for sufferers in the early stages of the disease, brain connections, or synapses, can be strengthened and even replaced by absorbing enough of the right nutrients. A UK-wide trail helps sufferers in the early stages to concentrate on improving everyday tasks, and in the process not only make their lives easier, but helps to reactivate the planning and organisational parts of the brain. In an ageing world, where the biggest risk of developing Alzheimer's is old age, the scientific breakthroughs in Alzheimer's disease are bringing hope where once there was despair.