Growing up in the streets of Dundee, actor Brian Cox was surrounded by tobacco. His entire family either smoked it or chewed it and yet Brian reveals, he never took up the habit. To find out why not, Brian travels to Virginia in the US to discover how the habit of smoking kick-started the British Empire and created a global market of addicts.
Specialist maxillofacial surgeons Tim Martin and Sat Parmar prepare for a marathon operation on 53-year-old Teresa. Four weeks ago, Teresa was diagnosed with a fast-growing cancerous tumour in her face and she will die within weeks unless it is removed. The procedure involves radical surgery to the entire right-hand side of her face, and means she will lose both her upper jaw and right eye. It is an enormous undertaking for Teresa, and for Tim and Sat, too. Using 3D imaging, the team plan how to remove the tumour and, most importantly, how they will rebuild Teresa's face. Tim and Sat are all too aware that whilst removing the tumour will save her life, it will be devastating if she is left disfigured and unable to face the world. To give her the best possible outcome, they intend to fill the cavity left in Teresa's face with a section of bone and muscle removed from her hip, using a 3D-printed plastic guide that helps them cut out the correct shape bone.
Panorama looks at the breakthrough that could change the lives of everyone and everything on the planet. Gene editing is revolutionising medical research and could deliver new treatments - even cures for a host of diseases. It also gives scientists control over evolution, allowing genetic changes to be forced through species. But some are worried about letting the gene genie out of the bottle.
Not all the microbes that live on us or inside us are benign, and it is only thanks to the superhuman nature of our bodies that we survive constant attack. However, humans are becoming increasingly vulnerable to disease. This programme examines the dramatic increase in allergic diseases such as asthma, eczema and hayfever.