Stephen Nolan lifts the curtain on the stigma surrounding depression and gains a better understanding of this illness. He meets people whose life is a constant battle against it and examines the science behind this potentially life-threatening condition.
Thought of as a modern phenomenon, it actually started over 400 years ago with a spate of botched nose jobs. Since then, surgeons have been entranced with the idea that not only could they fix the body, but could even fix our sense of self-esteem. Presenter Michael Mosley undergoes both 16th-century bondage and 21st-century botox in his journey of discovery.
Many clinical trials target the nation's most acute health issues. With deaths from liver disease soaring by 40 per cent in a decade, more and more patients are waiting for vital liver transplants. There is a shortage of organ donors and many donated organs are rejected as only those in excellent condition are considered suitable for a transplant procedure. Surgeons Richard Laing and Thamara Perera are part of a team at QEHB trialling a revolutionary way to tackle this crisis, by maximising the number of donor organs that can be safely re-used. The film follows the trial every step of the way, as Richard receives a donor liver that would usually be rejected and tries to prove it is viable for transplant by rejuvenating and testing it on a perfusion machine. This machine sustains the liver by mimicking the supply of blood, oxygen and nutrients an organ receives inside a live, healthy human body. Once the donor liver has proved itself fit for transplant, the surgical team start to remove grandmother Connie O'Driscoll's severely diseased liver. Once the donor liver has been disconnected from the perfusion machine, they have just 20 minutes to place it in Connie's body and plumb it into the complex and delicate network of hepatic blood vessels.
At an extraordinary moment in the history of one of the world’s oldest and most controversial drugs, Horizon investigates the very latest medical and scientific research into the effects of cannabis on the brain and the body. Medicinal cannabis became legal in the UK on 1 November 2018, but it is still shrouded in controversy. A&E doctor Javid Abdelmoneim wants to find out whether it will help or harm patients. Javid meets the young epilepsy patient responsible for changing the law around medicinal cannabis in the UK and sees the remarkable effects it has on his condition. He visits a medicinal cannabis farm in Denmark to learn how a company known for growing the recreational drug are now producing medicinal cannabis to be exported all over Europe. He travels to Israel, to find out why they have been using cannabis as a medicine for over 20 years and meets the scientists studying the safety and effectiveness of cannabis in treating pain. And he meets the so-called godfather of cannabis, who at 88 years old is still an active research scientist and considered the world’s leading cannabis expert. In the UK Javid encounters the first British patient to be prescribed intoxicating herbal cannabis to treat her chronic condition. He meets psychiatrists at King’s College London who reveal their new study linking cannabis more strongly than ever to alarming mental health problems. And he takes part in a groundbreaking trial looking at the effects of the different chemicals in cannabis on the brain.
According to current estimates, a widely available COVID-19 vaccine will likely be available within the next 12 months. Why so long? Learn how vaccines are developed and explore the current state of the coronavirus landscape, guided by the scientists on the ground trying to find a solution.