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Alzheimer’s disease strikes at the core of what makes us human: our capacity to think, to love, and to remember. The disease ravages the minds of over 40 million victims worldwide, and it is one of the greatest medical mysteries of our time. Join investigators as they gather clues and attempt to reconstruct the molecular chain of events that ultimately leads to dementia, and follow key researchers in the field who have helped to develop the leading theories of the disease. Along the way, meet individuals from all walks of life who will reveal what it’s like to struggle with Alzheimer’s. Among them, members of a unique Colombian family who have learned that their genetic predisposition all but guarantees early onset Alzheimer’s. Yet there may be hope. Join these courageous patients participating in clinical trials, and then go behind the scenes of the major drug trials to see how researchers target and test therapies that may slow and even prevent Alzheimer’s.
In this episode I visit a researcher who is studying memory by using machine learning and neuroimaging to detect and predict people's brain states. I also travel to Japan to meet with a team working on ways to record the content of peoples’ dreams.
S3E8 • Mind Field • 2019 • Brain
A baby's brain is a mystery whose secrets scientists are just beginning to unravel. The mystery begins in the womb -- only four weeks into gestation the first brain cells, the neurons, are already forming at an astonishing rate: 250,000 every minute.
1/5 • The Secret Life of the Brain • 2002 • Brain
Most of us think that Obsessive Compulsive Disorder (OCD) is just over fussy tidying. But it's actually much more serious. Sophie has to check that she hasn't killed people, looking for dead bodies wherever she goes, Richard is terrified of touching the bin, and Nanda is about to have pioneering brain surgery to stop her worrying about components on her body - that her eyebrow might not be aligned or that she has bad breath. Professor Uta Frith meets the people living with OCD, looks at the therapy available and asks what neuroscience can offer by way of a cure.
Rhod Gilbert is painfully shy. He might hide it well, but he can't even go into a cafe to buy a coffee. No joke. In fact, his social anxiety has had a massive effect on his life. Rhod's going to try find out why and what can be done. Talking to fellow shy comedian Greg Davies, other shy sufferers, and scientists, Rhod comes up with a radical solution for how we can all stand up to shyness. Rhod can stand up in front of 20,000 people and make them laugh for two hours solid. But he has always found it virtually impossible to talk to people one to one. From childhood, it has been a life-limiting condition. And in this Rhod is certainly not alone. It is estimated that nearly half the population in the UK have some manifestation of shyness and social anxiety. For many it is a minor irritation, for some it is a condition that can virtually destroy a life.
2018 • Brain
Have you noticed how the full moon looks bigger on the horizon than high overhead? Actually, the two images are exactly the same size -- so why do we perceive them differently? Scientists aren't sure, but there are plenty of intriguing theories. Andrew Vanden Heuvel unravels the details of focus, distance and proportion that contribute to this mystifying optical illusion.