The latest discoveries in neuroscience present a new view of how the brain ages. Overturning decades of dogma, scientists recently discovered that even into our seventies, our brains continue producing new neurons. Scientists no longer hold the longstanding belief that we lose vast numbers of brain cells as we grow older. The normal aging process leaves most mental functions intact, and may even provide the brain with unique advantages that form the basis for wisdom. The aging brain is also far more resilient than was previously believed.
Could the power of fake pills be used to treat some of our most common medical complaints? To find out, Dr Michael Mosley embarks on Britain's largest ever trial to investigate the placebo effect. He is heading to Blackpool to gather 117 people suffering from backache - one of the leading types of chronic pain - before trying to treat them with nothing but fake pills and the power of the mind. Working with experts from the University of Oxford, Michael discovers that the placebo effect is more than just a medical curiosity. The brain is actually capable of producing its own drugs, and these can be more powerful than prescription painkillers. Michael's volunteers come from all walks of life, but they have all suffered with bad backs for years and feel their conventional medication isn't up to the job. They include Stacey, who is struggling to keep up with her two energetic daughters, wheelchair user Jim, who longs to be able to get back on a boat, and poker player Moyra, who is looking for a painkiller which doesn't affect her performance. They think they are taking part in the trial of a powerful new painkiller, but their blue and white capsules actually contain nothing but ground-up rice. Can this fake treatment make a real difference? And how will the volunteers react when Michael reveals the truth? Michael also finds out about some remarkable placebo experiments from around the world, including a woman in Oxfordshire who experienced a near-miraculous recovery after undergoing fake surgery to fix her chronic shoulder pain. Plus a team in Lancashire who want to see if the placebo effect can cure a broken heart. And Michael discovers a team in Germany working on a placebo that works even if you know you are taking it, which might improve the lives of transplant patients. Michael also tests this out on himself - attempting to train his own body to respond to a fake treatment - a foul-tasting green drink - as if he were taking actual drugs.
Rhod Gilbert is painfully shy. He might hide it well, but he can't even go into a cafe to buy a coffee. No joke. In fact, his social anxiety has had a massive effect on his life. Rhod's going to try find out why and what can be done. Talking to fellow shy comedian Greg Davies, other shy sufferers, and scientists, Rhod comes up with a radical solution for how we can all stand up to shyness. Rhod can stand up in front of 20,000 people and make them laugh for two hours solid. But he has always found it virtually impossible to talk to people one to one. From childhood, it has been a life-limiting condition. And in this Rhod is certainly not alone. It is estimated that nearly half the population in the UK have some manifestation of shyness and social anxiety. For many it is a minor irritation, for some it is a condition that can virtually destroy a life.
2018 • Brain
Would you reroute a train to run over one person to prevent it from running over five others? In the classic “Trolley Problem” survey, most people say they would. But I wanted to test what people would actually do in a real-life situation. In the world’s first realistic simulation of this controversial moral dilemma, unsuspecting subjects will be forced to make what they believe is a life-or-death decision.
Comedian and impressionist Rory Bremner is on a personal mission to uncover the science of ADHD (attention deficit hyperactivity disorder), a condition which he has suspected he has. In this film, Rory learns about the science of ADHD, goes for a diagnosis and tries the drug methylphenidate (also known as Ritalin) for the first time - just before walking on stage. Around three per cent of the adult population suffer from ADHD (and five per cent of children), yet many people remain sceptical of its existence, blaming it on naughty children or bad parenting.