Alzheimer's disease -- the most feared of all maladies, with no way to cure, stop or even slow its insidious progression. But now, after decades of perseverance in the lab, researchers are on the cusp of a scientific breakthrough that could be the first step toward making Alzheimer's itself a distant memory. In the gripping new documentary Turning Point, acclaimed filmmaker James Keach takes us inside the quest for the first medication that that could treat the underlying process of Alzheimer's disease, more than a century after Dr. Alois Alzheimer first described the brain disorder that slowly destroys memory and cognitive skills. Along the way, we meet the people behind these grand experiments, the scientists driven as much by personal conviction as professional innovation. And we discover why medical science is never easy, often unpredictable and potentially perilous.
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In part 2, Prof. Arthur Shapiro takes us through visual illusions that show how our brain processes retinal impressions from light and dark. Watch as things "move" while they are standing still. It will be hard to believe your eyes after watching this program!
Could the power of fake pills be used to treat some of our most common medical complaints? To find out, Dr Michael Mosley embarks on Britain's largest ever trial to investigate the placebo effect. He is heading to Blackpool to gather 117 people suffering from backache - one of the leading types of chronic pain - before trying to treat them with nothing but fake pills and the power of the mind. Working with experts from the University of Oxford, Michael discovers that the placebo effect is more than just a medical curiosity. The brain is actually capable of producing its own drugs, and these can be more powerful than prescription painkillers. Michael's volunteers come from all walks of life, but they have all suffered with bad backs for years and feel their conventional medication isn't up to the job. They include Stacey, who is struggling to keep up with her two energetic daughters, wheelchair user Jim, who longs to be able to get back on a boat, and poker player Moyra, who is looking for a painkiller which doesn't affect her performance. They think they are taking part in the trial of a powerful new painkiller, but their blue and white capsules actually contain nothing but ground-up rice. Can this fake treatment make a real difference? And how will the volunteers react when Michael reveals the truth? Michael also finds out about some remarkable placebo experiments from around the world, including a woman in Oxfordshire who experienced a near-miraculous recovery after undergoing fake surgery to fix her chronic shoulder pain. Plus a team in Lancashire who want to see if the placebo effect can cure a broken heart. And Michael discovers a team in Germany working on a placebo that works even if you know you are taking it, which might improve the lives of transplant patients. Michael also tests this out on himself - attempting to train his own body to respond to a fake treatment - a foul-tasting green drink - as if he were taking actual drugs.
How can a lie become true? In this episode, Dr. Aaron Blaisdell and I create a game show that is actually a giant “human Skinner Box” to observe the formation of superstitious beliefs. And Dr. Samuel Veissière helps me design and perform a placebo reverse exorcism, harnessing the power of belief in both science and religion to convince normal people that a spirit has possessed their bodies.
Comedian and impressionist Rory Bremner is on a personal mission to uncover the science of ADHD (attention deficit hyperactivity disorder), a condition which he has suspected he has. In this film, Rory learns about the science of ADHD, goes for a diagnosis and tries the drug methylphenidate (also known as Ritalin) for the first time - just before walking on stage. Around three per cent of the adult population suffer from ADHD (and five per cent of children), yet many people remain sceptical of its existence, blaming it on naughty children or bad parenting.
Artificially intelligent machines are taking over. They’re influencing our everyday lives in profound and often invisible ways. They can read handwriting, interpret emotions, play games, and even act as personal assistants. They are in our phones, our cars, our doctors’ offices, our banks, our web searches…the list goes on and is rapidly growing ever longer. But how does today’s A.I. actually work—and is it truly intelligent? And for that matter, what is intelligence? The world’s brightest computer programmers are trying to build brighter machines by reverse-engineering the brain and by inventing completely new kinds of computers, with exponentially greater speed and processing power. NOVA Wonders looks at how far we’ve come and where machines are headed as their software becomes ever more…cerebral. How close are we from a world in which computers take over—from diagnosing cancer to driving our cars to targeting weapons? If we place more and more of our lives under the control of these artificial brains, what are we putting at risk?