Our Genes: Under Influence • 2016

58:39

Horizon investigates a new era of Alzheimer's research, which is bringing hope to millions of sufferers across the world. New scanning and gene technology is allowing scientists to identify the disease at its earliest stages, often 15 years before symptoms appear and the brain cells are destroyed. A series of new drugs trials in Colombia, the USA and Europe are showing startling success in reducing beta amyloid, the protein which is a hallmark of the disease. It is also becoming clear that changes in lifestyle can prevent the development of the disease. A new system inside the brain has been discovered which clears amyloid when we are in deep sleep, but allows it to accumulate if we don't sleep well. The programme reveals that for sufferers in the early stages of the disease, brain connections, or synapses, can be strengthened and even replaced by absorbing enough of the right nutrients. A UK-wide trail helps sufferers in the early stages to concentrate on improving everyday tasks, and in the process not only make their lives easier, but helps to reactivate the planning and organisational parts of the brain. In an ageing world, where the biggest risk of developing Alzheimer's is old age, the scientific breakthroughs in Alzheimer's disease are bringing hope where once there was despair.

Horizon • 2016 • Health

45:02

Youth may be wasted on the young, but luckily, you can buy it back. People are using everything from face-lifts to second skin tech to keep their youthful advantage. However, with so many unproven therapies on the market, how many actually work?

S1E2 • A User's Guide to Cheating Death • 2017 • Health

57:28

By the middle of January many people struggle to keep up their resolutions to be more active. The result is that the UK wastes nearly £600 million a year on unused gym memberships. But new science has the answers. Medical journalist Michael Mosley teams up with scientists whose latest research is turning common knowledge about fitness on its head. They reveal why 10,000 steps is just a marketing ploy and that two minutes of exercise is all a person needs each week. They discover how to get people to stick to their fitness plans and what exercise can actually make everyone more intelligent. Whether it is for couch potatoes who hate the thought of exercise, someone too busy to consider the gym, or even for fitness fanatics who are desperate to do more - science can help everyone exercise better.

2020 • Health

82:38

Nearly one-third of adults engage in problem drinking at some point in their lives. Health professionals assess drinkers at risk on a spectrum ranging from low-risk to an alcohol use disorder that can range from mild to severe. Risky Drinking challenges viewers to recognize when their drinking may be putting them at risk and offers information that could help millions of people lead healthier lives. Through case studies and expert analysis, the film investigates the broad spectrum of risky drinking at different ages and stages in people’s lives,

2017 • Health

58:37

For centuries scientists have been attempting to come up with an elixir of youth. Now remarkable discoveries are suggesting that ageing is something flexible that can ultimately be manipulated.

Horizon • Health

59:15

At an extraordinary moment in the history of one of the world’s oldest and most controversial drugs, Horizon investigates the very latest medical and scientific research into the effects of cannabis on the brain and the body. Medicinal cannabis became legal in the UK on 1 November 2018, but it is still shrouded in controversy. A&E doctor Javid Abdelmoneim wants to find out whether it will help or harm patients. Javid meets the young epilepsy patient responsible for changing the law around medicinal cannabis in the UK and sees the remarkable effects it has on his condition. He visits a medicinal cannabis farm in Denmark to learn how a company known for growing the recreational drug are now producing medicinal cannabis to be exported all over Europe. He travels to Israel, to find out why they have been using cannabis as a medicine for over 20 years and meets the scientists studying the safety and effectiveness of cannabis in treating pain. And he meets the so-called godfather of cannabis, who at 88 years old is still an active research scientist and considered the world’s leading cannabis expert. In the UK Javid encounters the first British patient to be prescribed intoxicating herbal cannabis to treat her chronic condition. He meets psychiatrists at King’s College London who reveal their new study linking cannabis more strongly than ever to alarming mental health problems. And he takes part in a groundbreaking trial looking at the effects of the different chemicals in cannabis on the brain.

Horizon • 2019 • Health