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Horizon investigates a new era of Alzheimer's research, which is bringing hope to millions of sufferers across the world. New scanning and gene technology is allowing scientists to identify the disease at its earliest stages, often 15 years before symptoms appear and the brain cells are destroyed. A series of new drugs trials in Colombia, the USA and Europe are showing startling success in reducing beta amyloid, the protein which is a hallmark of the disease. It is also becoming clear that changes in lifestyle can prevent the development of the disease. A new system inside the brain has been discovered which clears amyloid when we are in deep sleep, but allows it to accumulate if we don't sleep well. The programme reveals that for sufferers in the early stages of the disease, brain connections, or synapses, can be strengthened and even replaced by absorbing enough of the right nutrients. A UK-wide trail helps sufferers in the early stages to concentrate on improving everyday tasks, and in the process not only make their lives easier, but helps to reactivate the planning and organisational parts of the brain. In an ageing world, where the biggest risk of developing Alzheimer's is old age, the scientific breakthroughs in Alzheimer's disease are bringing hope where once there was despair.
Presenter Michael Mosley finds out how the early days of surgery were dark and barbaric, when the surgeon’s knife was more likely to kill you than save you, and invasive medicine generally meant being bloodlet by leeches to within an inch of your life.
5 • Blood and Guts: A History of Surgery • 2009 • Health
100 years ago a new word in medicine was invented: “vitamin". This year the world will spend over $100 billion on vitamins and supplements. Dr. Derek Muller takes us on a world-spanning investigation of vitamin science and history, asking how do we decide whether to take vitamin supplements or not?
2018 • Health
For 70 years we've waged war against harmful bacteria using antibiotics. But bacteria are fighting back and today more and more bacterial infections are becoming resistant to antibiotics. Drug-resistant superbugs are spreading; not just MRSA - also TB, pneumonia, e-coli. In Britain, hundreds are already dying of these infections - mainly the very young or the frail and elderly. But experts warn that unless we crack the problem, by 2050 we'll be facing a massive health crisis with over 10 million people dying of resistant bacterial infection worldwide every year.
2017 • Health
Explained examines why diets are often unsuccessful. It looks at the science that suggests that low carb, low fat, and body type diets as well as supplements and detoxification regimes simple do not work in helping most people lose weight. While the diet industry pushes us to avoid calories the food industry encourage us to eat more of them.
Beneath your ribs, you’ll find, among other things, the pancreas -- an organ that works a lot like a personal health coach.