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Stem cells found in the bone marrow are crucial for our health because they are needed to become new blood cells that sustain and protect our bodies. But when the transformation goes wrong, harmful mutations can cause the cells to start replicating without control -- a type of cancer known as leukemia. Danilo Allegra and Dania Puggioni explain how this happens and how certain treatments provide hope for those suffering from the disease.
What does it take to flush all the bad stuff from your body after a week-long bender? Or after several years of eating junk food? Can you atone for your health sins and start fresh?
1/6 • A User's Guide to Cheating Death • 2017 • Health
Thought of as a modern phenomenon, it actually started over 400 years ago with a spate of botched nose jobs. Since then, surgeons have been entranced with the idea that not only could they fix the body, but could even fix our sense of self-esteem. Presenter Michael Mosley undergoes both 16th-century bondage and 21st-century botox in his journey of discovery.
4 • Blood and Guts: A History of Surgery • 2009 • Health
Two procedures so formidable, they would not have been attempted even a few years ago. Surgical teams at the Queen Elizabeth are constantly pushing the limits of what is possible. But despite state-of-the-art diagnostic scanning, sometimes cancer surgeons don't know exactly what they are up against until they open the patient up on the operating table. Even with the most meticulous planning, sometimes they must resort to taking critical decisions live in the theatre. 74-year-old Jasmine Harkness has been referred to the specialist sarcoma unit with a vast tumour in her abdomen, weighing more than three stone - a third of her total body weight. It is consuming her, displacing organs including her stomach and liver. Unless it can be removed, she has just four weeks to live. Sarcoma specialists Sam Ford and Professor David Gourevitch can't be sure whether they will be able to save Jasmine until they open her up and inspect her anatomy. Such is the risk of this surgery - five years ago they would not have embarked on this intervention. Sue Sinclair, lead anaesthetist and matriarch of theatre, keeps the others in check - working alongside them as they battle to detach the tumour from Jasmine's organs and blood vessels, and remove it intact. Whenever it presses heavily on vital blood vessels, Jasmine's blood pressure plummets, placing her life in grave danger. It will take unwavering focus to keep her alive. The tumour has grown so invasively that it has crushed and displaced Jasmine's internal organs. Sam and David have a puzzle on their hands to identify what and where everything is. At times, dark humour is the only way to release the tension as they grapple with blood, guts and mind-boggling complexity.
2/3 • Surgeons: At the Edge of Life • 2018 • Health
Following reports that taking extra vitamins is pointless and possibly even dangerous, Gloria discovers whether the vitamins she takes each day are really necessary or if she can get all the nutrients she needs from her food? Chris tests out a new meal plan to see what difference changing what you eat makes to how you power through the day, and even how you sleep.
S1E1 • Food: Truth or Scare • 2016 • Health
DNA testing is becoming more and more common. People are making important health and life decisions based off this data, despite these tests being largely inaccurate.
3/6 • A User's Guide to Cheating Death • 2017 • Health