Angela Rippon investigates the disease that took her mother's life and is now starting to affect her friends. She undergoes a series of tests to discover if she has any early signs of the disease and makes the difficult decision about whether to take a genetic test that could predict her future risk. Along the way, Angela finds out some of the surprising ways people can help to protect themselves. She discovers why getting a good night's sleep could help prevent Alzheimer's and how learning a new language might be more effective than any current drug treatment. Angela also visits a number of people who are living with the disease, including Bob, the husband of one of her oldest friends. She meets families that carry a gene for early-onset Alzheimer's and discovers how they could be the best hope of finding a cure for this devastating disease.
This week, we meet a girl whose heart has formed outside her ribcage, a man who can spend nine minutes underwater without taking a breath, a woman who is growing a second skeleton and a paralysed man who is regaining movement thanks to a chip implanted into his brain that can 'read' his brain signals.
Two procedures so formidable, they would not have been attempted even a few years ago. Surgical teams at the Queen Elizabeth are constantly pushing the limits of what is possible. But despite state-of-the-art diagnostic scanning, sometimes cancer surgeons don't know exactly what they are up against until they open the patient up on the operating table. Even with the most meticulous planning, sometimes they must resort to taking critical decisions live in the theatre. 74-year-old Jasmine Harkness has been referred to the specialist sarcoma unit with a vast tumour in her abdomen, weighing more than three stone - a third of her total body weight. It is consuming her, displacing organs including her stomach and liver. Unless it can be removed, she has just four weeks to live. Sarcoma specialists Sam Ford and Professor David Gourevitch can't be sure whether they will be able to save Jasmine until they open her up and inspect her anatomy. Such is the risk of this surgery - five years ago they would not have embarked on this intervention. Sue Sinclair, lead anaesthetist and matriarch of theatre, keeps the others in check - working alongside them as they battle to detach the tumour from Jasmine's organs and blood vessels, and remove it intact. Whenever it presses heavily on vital blood vessels, Jasmine's blood pressure plummets, placing her life in grave danger. It will take unwavering focus to keep her alive. The tumour has grown so invasively that it has crushed and displaced Jasmine's internal organs. Sam and David have a puzzle on their hands to identify what and where everything is. At times, dark humour is the only way to release the tension as they grapple with blood, guts and mind-boggling complexity.