A&E doctor Javid Abdelmoneim is on a mission to find out the truth about alcohol. In January, the government released its new alcohol guidelines. For men, the recommended weekly limit was cut by a third to 14 units per week, equivalent to about seven pints of beer, bringing it in line with the amount recommended for women. So what is behind the change? This is just one question of many that Javid aims to answer as he explores the science of drinking and the new evidence for the health risks of alcohol. Why do some people get drunk quicker than others? What is behind red wine's healthy reputation? Is a nightcap actually good for your sleep? Does lining your stomach work? And can alcohol actually make you eat more?
Thought of as a modern phenomenon, it actually started over 400 years ago with a spate of botched nose jobs. Since then, surgeons have been entranced with the idea that not only could they fix the body, but could even fix our sense of self-esteem. Presenter Michael Mosley undergoes both 16th-century bondage and 21st-century botox in his journey of discovery.
Specialist maxillofacial surgeons Tim Martin and Sat Parmar prepare for a marathon operation on 53-year-old Teresa. Four weeks ago, Teresa was diagnosed with a fast-growing cancerous tumour in her face and she will die within weeks unless it is removed. The procedure involves radical surgery to the entire right-hand side of her face, and means she will lose both her upper jaw and right eye. It is an enormous undertaking for Teresa, and for Tim and Sat, too. Using 3D imaging, the team plan how to remove the tumour and, most importantly, how they will rebuild Teresa's face. Tim and Sat are all too aware that whilst removing the tumour will save her life, it will be devastating if she is left disfigured and unable to face the world. To give her the best possible outcome, they intend to fill the cavity left in Teresa's face with a section of bone and muscle removed from her hip, using a 3D-printed plastic guide that helps them cut out the correct shape bone.
Michael Mosley and James Wong explore the effect that our food has on our most important and, in terms of energy consumption, our greediest organ. It influences our diet by generating cravings for foods such as fat - the most energy-rich food of them all. James heads off to Peru to reveal the surprising link that fat-rich, indulgent chocolate has with breast milk. Sometimes these cravings almost become an addiction - like coffee for example. So we visit a remarkable lab where a team is studying the effect of caffeine on bees and how that may help explain the hold that caffeinated drinks have over us. Together, Michael and James take on some of the hottest chillies on the planet to show what the burn does to our brains. Using the latest imaging techniques and incredibly detailed specialist photography, this is a whole new way of thinking about our relationship with food and the powerful effect it has on our minds.
We bring you a special episode, celebrating the award of this year's Nobel Prize in Physiology or Medicine to Tasuku Honjo, Distinguished Professor at Kyoto University. His basic research has led to the development and clinical applications of Opdivo, a groundbreaking new anti-cancer drug that works with immune cells. It has given hope to many cancer patients, and surprised clinical specialists. We'll explore what innovation Opdivo has brought to cancer treatment, and what challenges remain.
This programme explores the way our experiences shape our minds and bodies as we make the journey from the most helpless to the most sophisticated organism on earth. Dr Chris and Dr Xand van Tullekan uncover how we develop new skills - whether riding a bike or learning to walk.