Michael Mosley explores the latest science about how our personalities are created - and whether they can be changed. Despite appearances, Mosley is a pessimist who constantly frets about the future. He wants to worry less and become more of an optimist. He tries out two techniques to change this aspect of his personality - with surprising results. And he travels to the frontiers of genetics and neuroscience to find out about the forces that shape all our personalities.
After being diagnosed with a rare and deadly form of malignant melanoma - acral lentiginous melanoma - Dr George McGavin embarks on a highly emotional and deeply personal journey as he goes through treatment for his cancer. George’s treatment is targeted drug therapy, using drugs approved for use by the NHS only weeks before his diagnosis. During this journey, he is given unprecedented access to the process and science behind his medical treatment and diagnosis. He also meets some of the most highly regarded scientists in the field of cancer research in his quest to understand not just his disease but what the future holds as a whole for cancer treatment. Amongst them are Professor Sir Michael Stratton, director of the Wellcome Sanger Institute and chief executive officer of the Wellcome Genome Campus, whose work resulted in the discovery of the mutation in the B RAF gene responsible for his form of melanoma. George also travels to Houston, Texas to meet Professor James P Allison, winner of the 2018 Nobel Prize in Medicine, to find out about his pioneering work in the field of immunotherapy - the greatest breakthrough in cancer research in a century. Back home in his own hospital, he meets a unique group of stage four melanoma patients who owe their lives to Professor Allison’s work. Ultimately, his journey culminates when he receives his prognosis, after three months of treatment, which will determine his future. Will these groundbreaking drugs actually work?
2019 • Health
Explained examines why diets are often unsuccessful. It looks at the science that suggests that low carb, low fat, and body type diets as well as supplements and detoxification regimes simple do not work in helping most people lose weight. While the diet industry pushes us to avoid calories the food industry encourage us to eat more of them.
Fewer children in the United States are getting vaccinated. That’s bad news for those kids, and also for public health in general. Often, the response is to argue and debate and get angry at people who are we see as making terrible, irrational decisions. Instead of doing that, let’s use science to understand why this is happening in the first place.
100 years ago a new word in medicine was invented: “vitamin". This year the world will spend over $100 billion on vitamins and supplements. Dr. Derek Muller takes us on a world-spanning investigation of vitamin science and history, asking how do we decide whether to take vitamin supplements or not?
2018 • Health