Heart Transplant: A Chance to Live • 2018

100:14

Follows two patients through groundbreaking 'first in-human' trials for CAR T-cell therapy, a treatment described as the beginning of the end of cancer. Not allowed to meet and separated by two floors of a hospital, 53-year-old Graham and 18-year old-Mahmoud are nevertheless bound together by their commitment to the treatment and their faith in the science. Terminally ill, the trial represents their only option. How do their ages and life experiences affect their physical and emotional response? For Martin Pule, the scientist who has developed the treatment, the responsibility of curing patients is both exciting and daunting. He knows he stands on the cusp of a breakthrough that could radically change the way we treat cancer. At the heart of this film is the complex relationship between the patients and the clinical team. How much hope can the patients be given when they are effectively going into these trials as human guinea pigs? The patients and clinical team must weigh up hope with realism and their response is a profound and revealing reflection of the human condition.

2019 • Health

45:02

Obesity is one of America's biggest public health concerns. Two thirds of Americans are overweight or obese. The pressure to lose weight is intense and many are turning to surgical means to achieve results.

S1E4 • A User's Guide to Cheating Death • 2017 • Health

58:28

Many clinical trials target the nation's most acute health issues. With deaths from liver disease soaring by 40 per cent in a decade, more and more patients are waiting for vital liver transplants. There is a shortage of organ donors and many donated organs are rejected as only those in excellent condition are considered suitable for a transplant procedure. Surgeons Richard Laing and Thamara Perera are part of a team at QEHB trialling a revolutionary way to tackle this crisis, by maximising the number of donor organs that can be safely re-used. The film follows the trial every step of the way, as Richard receives a donor liver that would usually be rejected and tries to prove it is viable for transplant by rejuvenating and testing it on a perfusion machine. This machine sustains the liver by mimicking the supply of blood, oxygen and nutrients an organ receives inside a live, healthy human body. Once the donor liver has proved itself fit for transplant, the surgical team start to remove grandmother Connie O'Driscoll's severely diseased liver. Once the donor liver has been disconnected from the perfusion machine, they have just 20 minutes to place it in Connie's body and plumb it into the complex and delicate network of hepatic blood vessels.

S1E3 • Surgeons: At the Edge of Life • 2018 • Health

59:15

At an extraordinary moment in the history of one of the world’s oldest and most controversial drugs, Horizon investigates the very latest medical and scientific research into the effects of cannabis on the brain and the body. Medicinal cannabis became legal in the UK on 1 November 2018, but it is still shrouded in controversy. A&E doctor Javid Abdelmoneim wants to find out whether it will help or harm patients. Javid meets the young epilepsy patient responsible for changing the law around medicinal cannabis in the UK and sees the remarkable effects it has on his condition. He visits a medicinal cannabis farm in Denmark to learn how a company known for growing the recreational drug are now producing medicinal cannabis to be exported all over Europe. He travels to Israel, to find out why they have been using cannabis as a medicine for over 20 years and meets the scientists studying the safety and effectiveness of cannabis in treating pain. And he meets the so-called godfather of cannabis, who at 88 years old is still an active research scientist and considered the world’s leading cannabis expert. In the UK Javid encounters the first British patient to be prescribed intoxicating herbal cannabis to treat her chronic condition. He meets psychiatrists at King’s College London who reveal their new study linking cannabis more strongly than ever to alarming mental health problems. And he takes part in a groundbreaking trial looking at the effects of the different chemicals in cannabis on the brain.

Horizon • 2019 • Health

106:08

How and why what we eat is the cause of the chronic diseases that are killing us, and changing what we eat can save our lives one bite at a time.

2018 • Health

96:01

Examines the profound claim that most, if not all, of the degenerative diseases that afflict us can be controlled, or even reversed, by rejecting our present menu of animal-based and processed foods.

2011 • Health