The heart is the most symbolic organ of the human body. Throughout history it has been seen as the site of our emotions, the very centre of our being. But modern medicine has come to see the heart as just a pump; a brilliant pump, but nothing more. And we see ourselves as ruled by our heads and not our hearts. In this documentary, filmmaker David Malone asks whether we are right to take this view. He explores the heart's conflicting histories as an emotional symbol and a physical organ, and investigates what the latest science is learning about its structures, its capacities and its role. In the age-old battle of hearts and minds, will these new discoveries alter the balance and allow the heart to reclaim something of its traditional place at the centre of our humanity?
Follows two patients through groundbreaking 'first in-human' trials for CAR T-cell therapy, a treatment described as the beginning of the end of cancer. Not allowed to meet and separated by two floors of a hospital, 53-year-old Graham and 18-year old-Mahmoud are nevertheless bound together by their commitment to the treatment and their faith in the science. Terminally ill, the trial represents their only option. How do their ages and life experiences affect their physical and emotional response? For Martin Pule, the scientist who has developed the treatment, the responsibility of curing patients is both exciting and daunting. He knows he stands on the cusp of a breakthrough that could radically change the way we treat cancer. At the heart of this film is the complex relationship between the patients and the clinical team. How much hope can the patients be given when they are effectively going into these trials as human guinea pigs? The patients and clinical team must weigh up hope with realism and their response is a profound and revealing reflection of the human condition.
2019 • Health
What are the principles behind Homeopathy and does it work?
Angela Rippon investigates the disease that took her mother's life and is now starting to affect her friends. She undergoes a series of tests to discover if she has any early signs of the disease and makes the difficult decision about whether to take a genetic test that could predict her future risk. Along the way, Angela finds out some of the surprising ways people can help to protect themselves. She discovers why getting a good night's sleep could help prevent Alzheimer's and how learning a new language might be more effective than any current drug treatment. Angela also visits a number of people who are living with the disease, including Bob, the husband of one of her oldest friends. She meets families that carry a gene for early-onset Alzheimer's and discovers how they could be the best hope of finding a cure for this devastating disease.
2016 • Health
What's worse for us: sugar or fat? To answer the hottest question in nutrition, twin doctors Chris and Xand Van Tulleken go on month-long high-fat and high-sugar diets. The effects on their bodies are shocking and surprising. But they also discover that in the debate about fat and sugar, the real enemy might have been hiding in plain sight.