Alzheimer's disease is the most common cause of dementia, affecting over 40 million people worldwide. And though it was discovered over a century ago, scientists are still grappling for a cure.
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When we look at the sky, we have a flat, two-dimensional view. So how do astronomers figure the distances of stars and galaxies from Earth? Yuan-Sen Ting shows us how trigonometric parallaxes, standard candles and more help us determine the distance of objects several billion light years away from Earth.
2014 • Physics
One deck. Fifty-two cards. How many arrangements? Let's put it this way: Any time you pick up a well shuffled deck, you are almost certainly holding an arrangement of cards that has never before existed and might not exist again. Yannay Khaikin explains how factorials allow us to pinpoint the exact (very large) number of permutations in a standard deck of cards.
2014 • Math
Would mathematics exist if people didn't? Did we create mathematical concepts to help us understand the world around us, or is math the native language of the universe itself? Jeff Dekofsky traces some famous arguments in this ancient and hotly debated question.
2014 • Math
When you listen to music, multiple areas of your brain become engaged and active. But when you actually play an instrument, that activity becomes more like a full-body brain workout. What's going on? Anita Collins explains the fireworks that go off in musicians' brains when they play, and examines some of the long-term positive effects of this mental workout.
Every day, we move and operate within systems of power that other people have constructed. But we’re often uncomfortable talking about power. Why? Eric Liu describes the six sources of power and explains how understanding them is key to being an effective citizen.
The shape, contents and future of the universe are all intricately related. We know that it's mostly flat; we know that it's made up of baryonic matter (like stars and planets), but mostly dark matter and dark energy; and we know that it's expanding constantly, so that all stars will eventually burn out into a cold nothingness. Renée Hlozek expands on the beauty of this dark ending.
Traveling is extremely arduous for microscopic sperm -- think of a human trying to swim in a pool made of...other humans.
When you breathe, you transport oxygen to the body’s cells to keep them working, while also clearing your system of the carbon dioxide that this work generates. How do we accomplish this crucial and complex task without even thinking about it? Emma Bryce takes us into the lungs to investigate how they help keep us alive.
Our skin is the largest organ in our bodies, with a surface area of about 20 square feet in adults. When we are cut or wounded, our skin begins to repair itself through a complex, well-coordinated process. Sarthak Sinha takes us past the epidermis and into the dermis to investigate this regenerative response.
One of the most significant scientific discoveries of the early 21st century is surely the Higgs boson, but the boson and the Higgs Field that allows for that magic particle are extremely difficult to grasp. Don Lincoln outlines an analogy (originally conceived by David Miller) that all of us can appreciate, starring a large dinner party, a raucous group of physicists, and Peter Higgs himself.
Austrian physicist Erwin Schrödinger, one of the founders of quantum mechanics, posed this famous question: If you put a cat in a sealed box with a device that has a 50% chance of killing the cat in the next hour, what will be the state of the cat when that time is up?
One of the most amazing facts in physics is that everything in the universe, from light to electrons to atoms, behaves like both a particle and a wave at the same time. But how did physicists arrive at this mind-boggling conclusion?
When you think about Einstein and physics, E=mc^2 is probably the first thing that comes to mind. But one of his greatest contributions to the field actually came in the form of an odd philosophical footnote in a 1935 paper he co-wrote -- which ended up being wrong.
The classical physics that we encounter in our everyday, macroscopic world is very different from the quantum physics that governs systems on a much smaller scale (like atoms).
How do we know what matter is made of? The quest for the atom has been a long one, beginning 2,400 years ago with the work of a Greek philosopher and later continued by a Quaker and a few Nobel Prize-winning scientists. Theresa Doud details the history of atomic theory.?
As the narrative goes, fat is bad. Well, it's actually more nuanced than that. The type of fat you eat is more impactful on your health than the quantity. George Zaidan examines triglycerides, the varied molecules that make up fat, and how to identify which types of fat you are consuming.
How many times does the chorus repeat in your favorite song? How many times have you listened to that chorus? Repetition in music isn’t just a feature of Western pop songs, either; it’s a global phenomenon. Why? Elizabeth Hellmuth Margulis walks us through the basic principles of the ‘exposure effect,’ detailing how repetition invites us into music as active participants, rather than passive listeners.
In standard notation, rhythm is indicated on a musical bar line. But there are other ways to visualize rhythm that can be more intuitive. John Varney describes the ‘wheel method’ of tracing rhythm and uses it to take us on a musical journey around the world.
When you picture the lowest levels of the food chain, you might imagine herbivores happily munching on lush, living green plants. But this idyllic image leaves out a huge (and slightly less appetizing) source of nourishment: dead stuff. John C. Moore details the "brown food chain," explaining how such unlikely delicacies as pond scum and animal poop contribute enormous amounts of energy to our ecosystems.
How do you know you’re real? Is existence all just a big dream? Has some mad scientist duped us into simply believing that we exist? James Zucker investigates all of these questions (and more) in this mind-boggling tribute to René Descartes’s "Meditations on First Philosophy."
Population statistics are like crystal balls -- when examined closely, they can help predict a country's future (and give important clues about the past). Kim Preshoff explains how using a visual tool called a population pyramid helps policymakers and social scientists make sense of the statistics, using three different countries' pyramids as examples.
Our planet was once populated by megafauna, big top-of-the-food-chain predators that played their part in balancing our ecosystems. When those megafauna disappear, the result is a "trophic cascade," where every part of the ecosystem reacts to the loss. How can we stay in balance? George Monbiot suggests rewilding: putting wolves, lions and other predators back on top -- with surprising results.
Light always travels at a speed of 299,792,458 meters per second. But if you're in motion too, you're going to perceive it as traveling even faster -- which isn't possible! In this second installment of a three-part series on space-time, CERN scientists Andrew Pontzen and Tom Whyntie use a space-time diagram to analyze the sometimes confounding motion of light.
The human eye is an amazing mechanism, able to detect anywhere from a few photons to a few quadrillion, or switch focus from the screen in front of you to the distant horizon in a third of a second. How did these complex structures evolve? Joshua Harvey details the 500 million year story of the human eye.
It’s 4am, and the big test is in 8 hours. You’ve been studying for days, but you still don’t feel ready. Should you drink another cup of coffee and spend the next few hours cramming? Or should you go to sleep? Shai Marcu defends the latter option, showing how sleep restructures your brain in a way that’s crucial for how our memory works.
The wheels in your brain are constantly turning, even when you're asleep or not paying attention. In fact, most of your brain’s activities are ones you’d never be aware of … unless they suddenly stopped. Nathan S. Jacobs takes us inside the always active, surprisingly spontaneous brain.
Earthquakes have always been a terrifying phenomenon, and they’ve become more deadly as our cities have grown — with collapsing buildings posing one of the largest risks. But why do buildings collapse in an earthquake? And how can it be prevented? Vicki V. May explains the physics of why it is not the sturdiest buildings, but the smartest, that will remain standing.
It's perfectly human to grapple with questions, like 'Where do we come from?' and 'How do I live a life of meaning?' These existential questions are central to the five major world religions -- and that's not all that connects these faiths. John Bellaimey explains the intertwined histories and cultures of Hinduism, Judaism, Buddhism, Christianity and Islam.
You can't help it; sometimes, you just get a bad feeling about someone that's hard to shake. So, what's happening in your brain when you make that critical (and often lasting) first judgment? Peter Mende-Siedlecki shares the social psychology of first impressions -- and why they may indicate that, deep down, people are basically good.
Imagine a game of dice: if the biggest number rolled is one, two, three, or four, player 1 wins. If the biggest number rolled is five or six, player 2 wins. Who has the best probability of winning the game? Leonardo Barichello explains how probability holds the answer to this seemingly counterintuitive puzzle.
Humans, octopi and pine trees alike are all made up of cells, tiny but sophisticated systems that keep life going. Cells are almost like tiny factories run by robots, with the nucleus, DNA, proteins, lipids, and vitamins and minerals all playing critical roles. George Zaidan and Charles Morton lay out the blueprint of a cell and explain how biochemistry binds all life together.
When you think of Archimedes’ Eureka moment, you probably imagine a man in a bathtub, right? As it turns out, there's much more to the story. Armand D'Angour tells the story of Archimedes' biggest assignment -- an enormous floating palace commissioned by a king -- that helped him find Eureka.
Why are most manhole covers round? Sure it makes them easy to roll, and slide into place in any alignment. But there’s another, more compelling reason, involving a peculiar geometric property of circles and other shapes. Marc Chamberland explains curves of constant width and Barbier’s theorem.
Stem cells found in the bone marrow are crucial for our health because they are needed to become new blood cells that sustain and protect our bodies. But when the transformation goes wrong, harmful mutations can cause the cells to start replicating without control -- a type of cancer known as leukemia. Danilo Allegra and Dania Puggioni explain how this happens and how certain treatments provide hope for those suffering from the disease.
Nestled in the tissues of your neck is a small, unassuming organ that wields enormous power over your body: the thyroid. Emma Bryce explains how the thyroid, like the operations manager in a company, is tasked with making sure that all the cells in your body are working properly.
We’ve all been told that we should recycle plastic bottles and containers. But what actually happens to the plastic if we just throw it away? Emma Bryce traces the life cycles of three different plastic bottles, shedding light on the dangers these disposables present to our world.
One hundred green-eyed logicians have been imprisoned on an island by a mad dictator. Their only hope for freedom lies in the answer to one famously difficult logic puzzle. Can you solve it? Alex Gendler walks us through this green-eyed riddle.
We hear about calories all the time: How many calories are in this cookie? How many are burned by doing 100 jumping jacks, or long-distance running, or fidgeting? But what is a calorie, really? And how many of them do we actually need? Emma Bryce explains how a few different factors should go into determining the recommended amount for each person.
2015 • Health
Has anyone ever told you, “Stand up straight!” or scolded you for slouching at a family dinner? Comments like that might be annoying—but they’re not wrong. Your posture is the foundation for every movement your body makes and can determine how well your body adapts to the stresses on it. Murat Dalkilinç gives the pros of good posture.
2015 • Health
Throughout the history of mankind, the subject of identity has sent poets to the blank page, philosophers to the agora and seekers to the oracles. These murky waters of abstract thinking are tricky to navigate, so it’s probably fitting that to demonstrate the complexity, the Greek historian Plutarch used the story of a ship.
2015 • Brain
Dolphins are one of the smartest animal species on Earth. In fact, their encephalization quotient (their brain size compared to the average for their body size) is second only to humans. But exactly how smart are they? Lori Marino details some incredible facts about dolphins.
2015 • Nature
In previous decades, most news with global reach came from several major newspapers and networks with the resources to gather information directly. The speed with which information spreads now, however, has created the ideal conditions for something called circular reporting. Noah Tavlin sheds light on this phenomenon.
2015 • People
When faced with a big challenge where potential failure seems to lurk at every corner, you’ve probably heard the advice, “Be more confident!” But where does confidence come from, and how can you get more of it? Here are three easy tips to boost your confidence.
2015 • Lifehack
Have you noticed how the full moon looks bigger on the horizon than high overhead? Actually, the two images are exactly the same size -- so why do we perceive them differently? Scientists aren't sure, but there are plenty of intriguing theories. Andrew Vanden Heuvel unravels the details of focus, distance and proportion that contribute to this mystifying optical illusion.
2013 • Brain
How can you tell the two poles apart? Where are the penguins? What about the bears? The Arctic pole is located in the Northern Hemisphere within the deep Arctic Ocean, while the Antarctic pole is smack in the middle of the ice-covered Antarctica. Camille Seaman describes how enterprising people and organisms have found ways to reside around both poles despite the frigid temperatures.
2013 • Nature
Imagine if you could plug your brain into a machine that would bring you ultimate pleasure for the rest of your life. The only catch? You have to permanently leave reality behind. Hayley Levitt and Bethany Rickwald explore Robert Nozick’s thought experiment that he called the Experience Machine.
2015 • Brain
Suppose you placed a camera at a fixed position, took a picture of the sky at the same time every day for an entire year, and overlaid all of the photos on top of each other. What would the sun look like in that combined image? A stationary dot? A circular path? Neither. Oddly enough, it makes a ‘figure 8’ pattern, known as the Sun’s analemma.
2015 • Astronomy
In the United States, it’s estimated that 30 percent of adults and 66 percent of adolescents are regularly sleep-deprived. This isn’t just a minor inconvenience: staying awake can cause serious bodily harm. Claudia Aguirre shows what happens to your body and brain when you skip sleep.
2015 • Health
Our hard-wired stress response is designed to gives us the quick burst of heightened alertness and energy needed to perform our best. But stress isn’t all good. When activated too long or too often, stress can damage virtually every part of our body. Sharon Horesh Bergquist gives us a look at what goes on inside our body when we are chronically stressed.
2015 • Health
Without water, a human can only survive for about 100 hours. But there’s a creature so resilient that it can go without it for decades. This 1-millimeter animal can survive both the hottest and coldest environments on earth, and can even withstand high levels of radiation. Thomas Boothby introduces us to the tardigrade, one of the toughest creatures on Earth.
2017 • Nature
They're cute, they're lovable, and judging by the 26 billion views on over 2 million YouTube videos of them, one thing is certain: cats are very entertaining. But their strange feline behaviors, both amusing and baffling, leave many of us asking: Why do cats do that? Tony Buffington explains the science behind some of your cat's strangest behaviors.
2016 • Science
Is sugar the new tobacco? How did the food industry get us to stop asking the question: is sugar toxic? It all starts with a secret PR campaign dating back to the 1970s. For forty years, Big Sugar deflected all threats to its multi-billion dollar empire, while sweetening the world's food supply. As obesity, diabetes, and heart disease rates skyrocket, doctors are now treating the first generation of children suffering from fatty liver disease. The sugar industry is once again under siege. They dodged the bullet once. Can they do it again?
2015 • Health
Is there any way to slow or even prevent the ravages of time? Veteran presenter Johnny Ball looks back over the 45 years that Horizon, and he, have been on air to find out what science has learned about how and why we grow old. Charting developments from macabre early claims of rejuvenation to the latest cutting-edge breakthroughs, Johnny discovers the sense of a personal mission that drives many scientists and asks whether we are really any closer to achieving the dream of immortality.
By 2050 the world’s population is estimated to reach over 9 billion, 30% larger than it currently is. If we continue to farm and eat the way we do today, we’d potentially need an additional landmass the size of Europe to produce enough food to meet the growing demand. So what does the future of food look like and how will we grow enough food for us all to eat in the years to come? In Tonight’s programme we visit some of the urban ventures that are maximising the use of public space to grow fruit and vegetables and teach the next generation how to farm. We speak to the owner of an indoor miniature farm housed inside a small shop about the new aquaponic technology he uses, and we go 100 feet below ground to see how one entrepreneur is growing high-value salad crops in old WWII bomb shelters, four storeys beneath the London Underground!
Dr Chris van Tulleken, Dr Hannah Fry and Michael Mosley examine the latest research and explore some of the big questions about Covid-19 and the pandemic it has created. Michael visits the UK government's high-security laboratory Porton Down, where vaccines are being tested. He also uncovers what the experience of the 2002 SARs epidemic reveals about this one. Both were caused by coronaviruses, but certain key changes to today's virus have allowed it to infect the world, where SARs was contained.
As a woman in New York City leans over a table, about to inhale a line of cocaine, she is unknowingly part of a $30 billion a year industry — an illegal empire governed by fear and violence, bribery and corruption, all spiraling out of control and turning Mexico and the southern border of the United States into one of the deadliest places on earth. In this probing, incisive investigation into the bloodstained path taken by cocaine we travel backwards from the end user in the U.S. all the way to the drug's source high in the South American mountains. We meet the dealers, traffickers, smugglers and farmers who together form its production and distribution chain, as well as the law enforcement agencies and individuals whose mission is to shut the deadly trade down. The cocaine industry is littered with unimaginable sums of cash and more than 35,000 murders in the past five years. Much of this violence occurs on the border between the United States and Mexico. This is just one aspect of the cocaine epidemic which is explored in the feature-length documentary Cocaine: History Between the Lines. This two-hour special goes inside the history of the second most used illicit drug in America. The human appetite for this narcotic goes all the way back to 3000 B.C., when South Americans chewed coca leaves thinking they were a gift from God. But it wasn't until 1855, when cocaine was first extracted from the coca leaf and used in powder form that its use spiked. Initially it was utilized as an anesthesia. Soon, famed psychologist Sigmund Freud touted it as an effective cure for depression and impotence. In 1886, John Pemberton, an Atlanta pharmacist, added it to his new soft drink: Coca Cola or Coke for short. In 1914, the drug was outlawed, but the damage had been done. The 70's ushered in another boost in the drug's use fueled in part by new drug cartels in South America. To combat cocaine's rise, the Reagan administration started the War on Drugs in the 80's. That hasn't stopped the proliferation of the drug in cities across America or with the cartels that continue to feed at the trough of this $30 billion dollar a year business. Cocaine use may have peaked decades ago, but it's never gone away. With the advent of crack cocaine in the 1980s, the trade became deadlier and more toxic than ever before. The high demand for the product has rendered more than 70% of Mexico under the control of the smuggling trade. American law enforcement agencies from Texas to California are fearful that this nefarious element will soon enter their country unchallenged. According to the officers interviewed in the film, border security is lax, and bureaucrats in Washington are doing little to remedy the crisis. For them, the discovery of a dismembered body – whether it be a trafficker, illegal immigrant or innocent bystander - has become a daily occurrence. This harsh reality is lost on most of the users themselves, who run the gamut from the hippest clubbers to the homeless population across America. Each user profiled in the film shares their experiences with the alluring white powder. Whether they use the drug recreationally or habitually, they have all witnessed the hold it can have on a life. From the personal to the political, Cocaine: History Between the Lines is a comprehensive account of a drug that has left much devastation in its wake.
2011 • Health
This time, we meet a man who feels no pain, a woman who can smell Parkinson's disease, a man who can remember every face he has ever seen and a survivor of a head injury who woke up to find he could suddenly play the piano. These remarkable cases are shedding new light on one of the most mysterious parts of the human body - our brain.