After being diagnosed with a rare and deadly form of malignant melanoma - acral lentiginous melanoma - Dr George McGavin embarks on a highly emotional and deeply personal journey as he goes through treatment for his cancer. George’s treatment is targeted drug therapy, using drugs approved for use by the NHS only weeks before his diagnosis. During this journey, he is given unprecedented access to the process and science behind his medical treatment and diagnosis. He also meets some of the most highly regarded scientists in the field of cancer research in his quest to understand not just his disease but what the future holds as a whole for cancer treatment. Amongst them are Professor Sir Michael Stratton, director of the Wellcome Sanger Institute and chief executive officer of the Wellcome Genome Campus, whose work resulted in the discovery of the mutation in the B RAF gene responsible for his form of melanoma. George also travels to Houston, Texas to meet Professor James P Allison, winner of the 2018 Nobel Prize in Medicine, to find out about his pioneering work in the field of immunotherapy - the greatest breakthrough in cancer research in a century. Back home in his own hospital, he meets a unique group of stage four melanoma patients who owe their lives to Professor Allison’s work. Ultimately, his journey culminates when he receives his prognosis, after three months of treatment, which will determine his future. Will these groundbreaking drugs actually work?
Sleep has long been regarded as nothing more than a way to charge our batteries. But what if it can control our weight, allow us to make memories, and help us to fight off diseases like Alzheimer’s? We travel the world to investigate how revolutionary new technology has revealed the sleeping brain as an energetic and purposeful machine.
2016 • Health
One in five families eat convenience foods at least three times a week and a government survey showed only one in six mothers cook from scratch every day. In the first of four food programmes over the next fortnight, the Tonight programme investigates why some of us can’t cook or won’t cook and what can be done to get Britain back in the kitchen. The UK has the largest consumption of ready meals in Europe. It’s no surprise; they are cheap, convenient and easy. A few minutes in a microwave and dinner is served. But for some families the ready meal isn’t always the first choice, it’s sometimes the only choice.
Dr Chris van Tulleken, Dr Hannah Fry and Michael Mosley examine the latest research and explore some of the big questions about Covid-19 and the pandemic it has created. Michael visits the UK government's high-security laboratory Porton Down, where vaccines are being tested. He also uncovers what the experience of the 2002 SARs epidemic reveals about this one. Both were caused by coronaviruses, but certain key changes to today's virus have allowed it to infect the world, where SARs was contained.