After being diagnosed with a rare and deadly form of malignant melanoma - acral lentiginous melanoma - Dr George McGavin embarks on a highly emotional and deeply personal journey as he goes through treatment for his cancer. George’s treatment is targeted drug therapy, using drugs approved for use by the NHS only weeks before his diagnosis. During this journey, he is given unprecedented access to the process and science behind his medical treatment and diagnosis. He also meets some of the most highly regarded scientists in the field of cancer research in his quest to understand not just his disease but what the future holds as a whole for cancer treatment. Amongst them are Professor Sir Michael Stratton, director of the Wellcome Sanger Institute and chief executive officer of the Wellcome Genome Campus, whose work resulted in the discovery of the mutation in the B RAF gene responsible for his form of melanoma. George also travels to Houston, Texas to meet Professor James P Allison, winner of the 2018 Nobel Prize in Medicine, to find out about his pioneering work in the field of immunotherapy - the greatest breakthrough in cancer research in a century. Back home in his own hospital, he meets a unique group of stage four melanoma patients who owe their lives to Professor Allison’s work. Ultimately, his journey culminates when he receives his prognosis, after three months of treatment, which will determine his future. Will these groundbreaking drugs actually work?
Just as humans have always sought food to survive, we have also sought the means to preserve that food. Right from the very moment of a kill or a harvest, food begins to break down. With preservation, we can plan for times of scarcity during times of plenty.
As the narrative goes, fat is bad. Well, it's actually more nuanced than that. The type of fat you eat is more impactful on your health than the quantity. George Zaidan examines triglycerides, the varied molecules that make up fat, and how to identify which types of fat you are consuming.
Renowned geneticist and author Spencer Wells reveals how changes in our genetic code have fueled major changes in our appearance and capabilities over time, and why scientists believe we're continuing to rapidly evolve today. By understanding these changes, we are better prepared for the future.
2018 • Health
Fewer children in the United States are getting vaccinated. That’s bad news for those kids, and also for public health in general. Often, the response is to argue and debate and get angry at people who are we see as making terrible, irrational decisions. Instead of doing that, let’s use science to understand why this is happening in the first place.
Nearly half of us take a vitamin or mineral supplement every day, but what are these pills sold on every high street actually doing for us? Digging deeper than the eye catching words on the packaging, Dr Giles Yeo investigates who really needs a supplement by putting our diets to the test.
The Ebola outbreak of 2014 almost brought the world to its knees, but this crisis has mobilized scientists and researchers, paving the way for new treatments and vaccines. From antibiotics and vaccines to computer programs that predict how viruses will spread, new lifesaving tools will be used to fight a wide range of viruses in the near future, including HIV, influenza, dengue fever, malaria, and a host of other killer diseases.