After being diagnosed with a rare and deadly form of malignant melanoma - acral lentiginous melanoma - Dr George McGavin embarks on a highly emotional and deeply personal journey as he goes through treatment for his cancer. George’s treatment is targeted drug therapy, using drugs approved for use by the NHS only weeks before his diagnosis. During this journey, he is given unprecedented access to the process and science behind his medical treatment and diagnosis. He also meets some of the most highly regarded scientists in the field of cancer research in his quest to understand not just his disease but what the future holds as a whole for cancer treatment. Amongst them are Professor Sir Michael Stratton, director of the Wellcome Sanger Institute and chief executive officer of the Wellcome Genome Campus, whose work resulted in the discovery of the mutation in the B RAF gene responsible for his form of melanoma. George also travels to Houston, Texas to meet Professor James P Allison, winner of the 2018 Nobel Prize in Medicine, to find out about his pioneering work in the field of immunotherapy - the greatest breakthrough in cancer research in a century. Back home in his own hospital, he meets a unique group of stage four melanoma patients who owe their lives to Professor Allison’s work. Ultimately, his journey culminates when he receives his prognosis, after three months of treatment, which will determine his future. Will these groundbreaking drugs actually work?
Is there any way to slow or even prevent the ravages of time? Veteran presenter Johnny Ball looks back over the 45 years that Horizon, and he, have been on air to find out what science has learned about how and why we grow old. Charting developments from macabre early claims of rejuvenation to the latest cutting-edge breakthroughs, Johnny discovers the sense of a personal mission that drives many scientists and asks whether we are really any closer to achieving the dream of immortality.
As the narrative goes, fat is bad. Well, it's actually more nuanced than that. The type of fat you eat is more impactful on your health than the quantity. George Zaidan examines triglycerides, the varied molecules that make up fat, and how to identify which types of fat you are consuming.
A&E doctor Javid Abdelmoneim is on a mission to find out the truth about alcohol. In January, the government released its new alcohol guidelines. For men, the recommended weekly limit was cut by a third to 14 units per week, equivalent to about seven pints of beer, bringing it in line with the amount recommended for women. So what is behind the change? This is just one question of many that Javid aims to answer as he explores the science of drinking and the new evidence for the health risks of alcohol. Why do some people get drunk quicker than others? What is behind red wine's healthy reputation? Is a nightcap actually good for your sleep? Does lining your stomach work? And can alcohol actually make you eat more?
2016 • Health
For thousands of years, we’ve regarded sleep as nothing more than an annihilation of consciousness. But there is one compelling fact that has always stood in the way of that view. “Even the Greek philosophers wondered why we needed to sleep,” says neuroscientist, Dr. Kenneth Wright. “If sleep wasn’t important, it’s probably one of the most significant mistakes that evolution ever made.” Yet decades of intense research have failed to discover the key function of sleep. But now, thanks to revolutionary new technology, innovative animal research and extraordinary advances in genetics, all that’s about to change. Join Dr. Jennifer Gardy as she goes on an extraordinary odyssey from a city that never sleeps to an isolation chamber in the Colorado Rockies, from one of the most unique research centres in the world to the world of dreams. Her goal is simple: Discover why we sleep