As a woman in New York City leans over a table, about to inhale a line of cocaine, she is unknowingly part of a $30 billion a year industry — an illegal empire governed by fear and violence, bribery and corruption, all spiraling out of control and turning Mexico and the southern border of the United States into one of the deadliest places on earth. In this probing, incisive investigation into the bloodstained path taken by cocaine we travel backwards from the end user in the U.S. all the way to the drug's source high in the South American mountains. We meet the dealers, traffickers, smugglers and farmers who together form its production and distribution chain, as well as the law enforcement agencies and individuals whose mission is to shut the deadly trade down. The cocaine industry is littered with unimaginable sums of cash and more than 35,000 murders in the past five years. Much of this violence occurs on the border between the United States and Mexico. This is just one aspect of the cocaine epidemic which is explored in the feature-length documentary Cocaine: History Between the Lines. This two-hour special goes inside the history of the second most used illicit drug in America. The human appetite for this narcotic goes all the way back to 3000 B.C., when South Americans chewed coca leaves thinking they were a gift from God. But it wasn't until 1855, when cocaine was first extracted from the coca leaf and used in powder form that its use spiked. Initially it was utilized as an anesthesia. Soon, famed psychologist Sigmund Freud touted it as an effective cure for depression and impotence. In 1886, John Pemberton, an Atlanta pharmacist, added it to his new soft drink: Coca Cola or Coke for short. In 1914, the drug was outlawed, but the damage had been done. The 70's ushered in another boost in the drug's use fueled in part by new drug cartels in South America. To combat cocaine's rise, the Reagan administration started the War on Drugs in the 80's. That hasn't stopped the proliferation of the drug in cities across America or with the cartels that continue to feed at the trough of this $30 billion dollar a year business. Cocaine use may have peaked decades ago, but it's never gone away. With the advent of crack cocaine in the 1980s, the trade became deadlier and more toxic than ever before. The high demand for the product has rendered more than 70% of Mexico under the control of the smuggling trade. American law enforcement agencies from Texas to California are fearful that this nefarious element will soon enter their country unchallenged. According to the officers interviewed in the film, border security is lax, and bureaucrats in Washington are doing little to remedy the crisis. For them, the discovery of a dismembered body – whether it be a trafficker, illegal immigrant or innocent bystander - has become a daily occurrence. This harsh reality is lost on most of the users themselves, who run the gamut from the hippest clubbers to the homeless population across America. Each user profiled in the film shares their experiences with the alluring white powder. Whether they use the drug recreationally or habitually, they have all witnessed the hold it can have on a life. From the personal to the political, Cocaine: History Between the Lines is a comprehensive account of a drug that has left much devastation in its wake.
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Of all the wonders of the human body, there's one more mysterious than any other. Blood: five precious litres that keep us alive. Yet how much do we really know about this sticky red substance and its mysterious, life-giving force?
The opioid epidemic has devastated America. But what is the situation here? A new report from Public Health England raises serious concerns about Britain's own relationship with painkillers. Dr Michael Mosley embarks on an immersive journey to Britain’s opioid frontline and meets patients struggling with addiction and GPs fighting a constant battle to help those suffering from chronic pain. He also uncovers worrying evidence of people abusing over-the-counter opioids and discovers how easy it is to buy strong opioids online.
Fat is not just stored energy, it’s a complex organ that controls crucial hormones and communicates with your brain, immune system, and metabolism. It's one of the most powerful organs, but it can be one of the most dangerous ones, as well. When there’s too much of it, fat can trigger inflammation, disrupt hormonal balance, increase your risk for nearly every major disease, and significantly shorten your life. What is fat really, and how does it function? When does it become dangerous and can the damage caused by excessive amounts of fat be reversed?
In a Nutshell • 2026 • Health
Michael Mosley and James Wong explore the effect that our food has on our most important and, in terms of energy consumption, our greediest organ. It influences our diet by generating cravings for foods such as fat - the most energy-rich food of them all. James heads off to Peru to reveal the surprising link that fat-rich, indulgent chocolate has with breast milk. Sometimes these cravings almost become an addiction - like coffee for example. So we visit a remarkable lab where a team is studying the effect of caffeine on bees and how that may help explain the hold that caffeinated drinks have over us. Together, Michael and James take on some of the hottest chillies on the planet to show what the burn does to our brains. Using the latest imaging techniques and incredibly detailed specialist photography, this is a whole new way of thinking about our relationship with food and the powerful effect it has on our minds.
S1E3 • The Secrets of Your Food • 2017 • Health