Powering the Mind • 2015 • episode "6/10" • Catalyst: Season 1

53:16

Alzheimer’s disease strikes at the core of what makes us human: our capacity to think, to love, and to remember. The disease ravages the minds of over 40 million victims worldwide, and it is one of the greatest medical mysteries of our time. Join investigators as they gather clues and attempt to reconstruct the molecular chain of events that ultimately leads to dementia, and follow key researchers in the field who have helped to develop the leading theories of the disease. Along the way, meet individuals from all walks of life who will reveal what it’s like to struggle with Alzheimer’s. Among them, members of a unique Colombian family who have learned that their genetic predisposition all but guarantees early onset Alzheimer’s. Yet there may be hope. Join these courageous patients participating in clinical trials, and then go behind the scenes of the major drug trials to see how researchers target and test therapies that may slow and even prevent Alzheimer’s.

NOVA PBS • 2016 • Brain

21:39

What happens to a brain on psychedelics? Turn on, tune in and drop out on this trip to explore the history and effects of mind-altering substances.

5/5 • The Mind, Explained • 2019 • Brain

4:02

Are we wholly responsible for our actions? We don’t choose our brains, our genetic inheritance, our circumstances, our milieu – so how much control do we really have over our lives? Philosopher Raoul Martinez argues that no one is truly blameworthy. Our most visionary scientists, psychologists and philosophers have agreed that we have far less free will than we think, and yet most of society’s systems are structured around the opposite principle – that we are all on a level playing field, and we all get what we deserve.

RSA Shorts • 2017 • Brain

54:23

When examining the adolescent brain we find mystery, complexity, frustration, and inspiration. As the brain begins teeming with hormones, the prefrontal cortex, the center of reasoning and impulse control, is still a work in progress. For the first time, scientists can offer an explanation for what parents already know -- adolescence is a time of roiling emotions, and poor judgment.

3/5 • The Secret Life of the Brain • 2002 • Brain

59:09

Rhod Gilbert is painfully shy. He might hide it well, but he can't even go into a cafe to buy a coffee. No joke. In fact, his social anxiety has had a massive effect on his life. Rhod's going to try find out why and what can be done. Talking to fellow shy comedian Greg Davies, other shy sufferers, and scientists, Rhod comes up with a radical solution for how we can all stand up to shyness. Rhod can stand up in front of 20,000 people and make them laugh for two hours solid. But he has always found it virtually impossible to talk to people one to one. From childhood, it has been a life-limiting condition. And in this Rhod is certainly not alone. It is estimated that nearly half the population in the UK have some manifestation of shyness and social anxiety. For many it is a minor irritation, for some it is a condition that can virtually destroy a life.

2018 • Brain

58:41

Could the power of fake pills be used to treat some of our most common medical complaints? To find out, Dr Michael Mosley embarks on Britain's largest ever trial to investigate the placebo effect. He is heading to Blackpool to gather 117 people suffering from backache - one of the leading types of chronic pain - before trying to treat them with nothing but fake pills and the power of the mind. Working with experts from the University of Oxford, Michael discovers that the placebo effect is more than just a medical curiosity. The brain is actually capable of producing its own drugs, and these can be more powerful than prescription painkillers. Michael's volunteers come from all walks of life, but they have all suffered with bad backs for years and feel their conventional medication isn't up to the job. They include Stacey, who is struggling to keep up with her two energetic daughters, wheelchair user Jim, who longs to be able to get back on a boat, and poker player Moyra, who is looking for a painkiller which doesn't affect her performance. They think they are taking part in the trial of a powerful new painkiller, but their blue and white capsules actually contain nothing but ground-up rice. Can this fake treatment make a real difference? And how will the volunteers react when Michael reveals the truth? Michael also finds out about some remarkable placebo experiments from around the world, including a woman in Oxfordshire who experienced a near-miraculous recovery after undergoing fake surgery to fix her chronic shoulder pain. Plus a team in Lancashire who want to see if the placebo effect can cure a broken heart. And Michael discovers a team in Germany working on a placebo that works even if you know you are taking it, which might improve the lives of transplant patients. Michael also tests this out on himself - attempting to train his own body to respond to a fake treatment - a foul-tasting green drink - as if he were taking actual drugs.

Horizon • 2018 • Brain