Anxiety • 2019 • episode "S1E3" • The Mind, Explained

41:31

Why do we hate? Humans are capable of love and cooperation --so why do we treat each other with cruelty and violence? Evolutionary anthropologist Brian Hare searches for the origins of hate in our distant past, and in our contemporary environment.

S1E1 • Why We Hate • 2019 • Brain

88:39

Alzheimer's disease -- the most feared of all maladies, with no way to cure, stop or even slow its insidious progression. But now, after decades of perseverance in the lab, researchers are on the cusp of a scientific breakthrough that could be the first step toward making Alzheimer's itself a distant memory. In the gripping new documentary Turning Point, acclaimed filmmaker James Keach takes us inside the quest for the first medication that that could treat the underlying process of Alzheimer's disease, more than a century after Dr. Alois Alzheimer first described the brain disorder that slowly destroys memory and cognitive skills. Along the way, we meet the people behind these grand experiments, the scientists driven as much by personal conviction as professional innovation. And we discover why medical science is never easy, often unpredictable and potentially perilous.

2020 • Brain

26:32

There are 100 billion individual neurons in the human brain. Working together, they allow us to make sense of, and move through, the world around us. Scientists have built replicas of the human brain with computers, but no one has ever successfully made a brain out of humans. On this episode, I’ll travel back to my hometown of Stilwell, Kansas, and turn it into a working brain!

S3E3 • Mind Field • 2018 • Brain

58:16

In the final episode Dr Alice Roberts explores how our species, homo sapiens, developed our large brain; and asks why we are the only one of our kind left on the planet today?

S1E3 • Origins of Us • Brain

58:41

Could the power of fake pills be used to treat some of our most common medical complaints? To find out, Dr Michael Mosley embarks on Britain's largest ever trial to investigate the placebo effect. He is heading to Blackpool to gather 117 people suffering from backache - one of the leading types of chronic pain - before trying to treat them with nothing but fake pills and the power of the mind. Working with experts from the University of Oxford, Michael discovers that the placebo effect is more than just a medical curiosity. The brain is actually capable of producing its own drugs, and these can be more powerful than prescription painkillers. Michael's volunteers come from all walks of life, but they have all suffered with bad backs for years and feel their conventional medication isn't up to the job. They include Stacey, who is struggling to keep up with her two energetic daughters, wheelchair user Jim, who longs to be able to get back on a boat, and poker player Moyra, who is looking for a painkiller which doesn't affect her performance. They think they are taking part in the trial of a powerful new painkiller, but their blue and white capsules actually contain nothing but ground-up rice. Can this fake treatment make a real difference? And how will the volunteers react when Michael reveals the truth? Michael also finds out about some remarkable placebo experiments from around the world, including a woman in Oxfordshire who experienced a near-miraculous recovery after undergoing fake surgery to fix her chronic shoulder pain. Plus a team in Lancashire who want to see if the placebo effect can cure a broken heart. And Michael discovers a team in Germany working on a placebo that works even if you know you are taking it, which might improve the lives of transplant patients. Michael also tests this out on himself - attempting to train his own body to respond to a fake treatment - a foul-tasting green drink - as if he were taking actual drugs.

Horizon • 2018 • Brain

59:15

The Psychedelic Drug Trial has exclusive access to a ground-breaking new trial at Imperial College London. The trial sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists, led by Professor David Nutt, Dr Robin Carhart-Harris and Dr Rosalind Watts, as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant (an SSRI called escitalopram) on a small group of participants with clinical depression. This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression.

2021 • Brain