Live Longer • 2017 • episode "S2E2" • Food: Truth or Scare

58:59

After being diagnosed with a rare and deadly form of malignant melanoma - acral lentiginous melanoma - Dr George McGavin embarks on a highly emotional and deeply personal journey as he goes through treatment for his cancer. George’s treatment is targeted drug therapy, using drugs approved for use by the NHS only weeks before his diagnosis. During this journey, he is given unprecedented access to the process and science behind his medical treatment and diagnosis. He also meets some of the most highly regarded scientists in the field of cancer research in his quest to understand not just his disease but what the future holds as a whole for cancer treatment. Amongst them are Professor Sir Michael Stratton, director of the Wellcome Sanger Institute and chief executive officer of the Wellcome Genome Campus, whose work resulted in the discovery of the mutation in the B RAF gene responsible for his form of melanoma. George also travels to Houston, Texas to meet Professor James P Allison, winner of the 2018 Nobel Prize in Medicine, to find out about his pioneering work in the field of immunotherapy - the greatest breakthrough in cancer research in a century. Back home in his own hospital, he meets a unique group of stage four melanoma patients who owe their lives to Professor Allison’s work. Ultimately, his journey culminates when he receives his prognosis, after three months of treatment, which will determine his future. Will these groundbreaking drugs actually work?

2019 • Health

91:09

Food Choices focuses on how the food we consume affects not only our personal health, but that of the entire planet. Filmmaker Michael Siewierski takes an in-depth look at how the consumption of animal products has a long-lasting, negative effect on the earth’s biosphere. Not only does he report on facts relating to the unethical treatment of animals raised for human consumption, but he also addresses the addition of genetically modified organisms (GMOs) and antibiotics to animal feed. This trickle-down effect results in the poisoning of both our bodies and the planet.

2016 • Health

59:07

Two procedures so formidable, they would not have been attempted even a few years ago. Surgical teams at the Queen Elizabeth are constantly pushing the limits of what is possible. But despite state-of-the-art diagnostic scanning, sometimes cancer surgeons don't know exactly what they are up against until they open the patient up on the operating table. Even with the most meticulous planning, sometimes they must resort to taking critical decisions live in the theatre. 74-year-old Jasmine Harkness has been referred to the specialist sarcoma unit with a vast tumour in her abdomen, weighing more than three stone - a third of her total body weight. It is consuming her, displacing organs including her stomach and liver. Unless it can be removed, she has just four weeks to live. Sarcoma specialists Sam Ford and Professor David Gourevitch can't be sure whether they will be able to save Jasmine until they open her up and inspect her anatomy. Such is the risk of this surgery - five years ago they would not have embarked on this intervention. Sue Sinclair, lead anaesthetist and matriarch of theatre, keeps the others in check - working alongside them as they battle to detach the tumour from Jasmine's organs and blood vessels, and remove it intact. Whenever it presses heavily on vital blood vessels, Jasmine's blood pressure plummets, placing her life in grave danger. It will take unwavering focus to keep her alive. The tumour has grown so invasively that it has crushed and displaced Jasmine's internal organs. Sam and David have a puzzle on their hands to identify what and where everything is. At times, dark humour is the only way to release the tension as they grapple with blood, guts and mind-boggling complexity.

S1E2 • Surgeons: At the Edge of Life • 2018 • Health

58:24

Michael Mosley and James Wong explore the effect that our food has on our most important and, in terms of energy consumption, our greediest organ. It influences our diet by generating cravings for foods such as fat - the most energy-rich food of them all. James heads off to Peru to reveal the surprising link that fat-rich, indulgent chocolate has with breast milk. Sometimes these cravings almost become an addiction - like coffee for example. So we visit a remarkable lab where a team is studying the effect of caffeine on bees and how that may help explain the hold that caffeinated drinks have over us. Together, Michael and James take on some of the hottest chillies on the planet to show what the burn does to our brains. Using the latest imaging techniques and incredibly detailed specialist photography, this is a whole new way of thinking about our relationship with food and the powerful effect it has on our minds.

S1E3 • The Secrets of Your Food • 2017 • Health

24:28

A groundbreaking medical reproductive procedure has made parenthood possible for millions around the world - but at what cost?

S2E9 • History 101 • 2022 • Health

58:46

Is there any way to slow or even prevent the ravages of time? Veteran presenter Johnny Ball looks back over the 45 years that Horizon, and he, have been on air to find out what science has learned about how and why we grow old. Charting developments from macabre early claims of rejuvenation to the latest cutting-edge breakthroughs, Johnny discovers the sense of a personal mission that drives many scientists and asks whether we are really any closer to achieving the dream of immortality.

Horizon • 2014 • Health